I've had a very strange bug come up twice now, and I have yet to find a solution.

When the administrator account signs into the website, all module content disapears...  The container still exists, I can edit properties of the module, but in all modules content is not returned in view or edit mode.  The host account works fine, and using it I created a new administrator account for the portal.  The new administrator account works fine, but the original admin account is broke.

This happened on a single portal in a single application on an application where I have a number of third party and custom desktop and HTTP modules, and I had no idea how to reproduce the issue on another system; so I haven't reported the problem yet, although it appeared a few months ago.

Just in the last two weeks i've had the same thing happen on a completely different installation.  This new installation is running core modules only (forums, blogs, text/html).  It was configured with all default settings...  

I tried upgrading to 4.6.2 but this did not solve the problem.

Has anybody else experienced anythign like this?