We upgraded to 4.5.2 today, but I would rather not have the Web/Site radio buttons on the search skin object. I would also rather have the text box and "search" text on the same line. Is there  a way to change this through the portal or do I need to modify the ascx file?

Funny, that wasn't in the Benefactors release.  
I see it now that I downloaded the public release. Looks like they have it using their own AdSense account, pretty sneaky. ;)

You can turn it off by adding a couple attributes to your search skinObject

<dnn:SEARCH runat="server" id="dnnSEARCH" showWeb="False" showSite="False" />

Also, if you want to use your own adsense account you can change the account number as outlined at the following link:

DNN 4.5.2 Web and Site Search radio buttons